Our lab is located on the first floor of the Vontz Center for Molecular Studies at the University of Cincinnati College of Medicine. The Vontz Center consists of 150,000 square feet with three floors of lab space, offices, lobby and lecture hall. The Vontz Center was designed by world renowned architect Frank O. Gehry and opened in 1999. The center has state of art equipment and core facilities for biochemical, proteomics, flow cytometry, real-time imaging and molecular biology research. We also have a state-of-art animal facility and animal imaging core within the building. We are actively integrated into several programs within the Cincinnati Children Hospital Medical Center (CCHMC) located adjacent to us. CCHMC is a top three children’s hospital in the US. We are also connected to the UC Cancer Institute, the UC Metabolic Disease Institute, the UC Neuroscience Institute and the Hoxworth Blood Center. We actively collaborate to study the impact of proteasome biology in hematologic malignancies and brain tumors. Being at this vibrant research community integrated with translational and clinical studies provides a unique opportunity to impact cancer research.